First broadcast in June 2006, 'Vitamin' aired it's final episode on March 9, where the members took some time to say their farewell messages. MC Lee Hwi Jae commented, "It's an old-fashioned saying but 'Vitamin' was like family to us. It hurts but reality is, nothing lasts forever. We would like to thank all the viewers for their kind support. We love you."

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MC and actor Kim Tae Hoon commented, "It was a like a supplement-type of program. I had a good time with good people."  Singer Hong Kyung Min, who participated in the panel discussion said, "It was a healthy adventure spending quality time with everyone and eating nutritious foods."

Singer Jang Yoon Jung and her husband Do Kyung Wan were MCs on the show, and said, "I told my wife to 'take it easy' when she was stressed out from work but it seems like she has to work harder now," making the audience laugh.